Abstract
The synthesis, biological activity, and pharmacokinetic profile of CCR1 antagonists are described.
MeSH terms
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Animals
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Dogs
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Haplorhini
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Humans
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Microsomes, Liver / metabolism
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Piperazines / chemical synthesis
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Piperazines / chemistry*
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Piperazines / metabolism*
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Rats
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Receptors, CCR1
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Receptors, Chemokine / antagonists & inhibitors*
Substances
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CCR1 protein, human
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Ccr1 protein, rat
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Piperazines
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Receptors, CCR1
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Receptors, Chemokine